The da Vinci 50

04/27/2020

“We were very pleased to find out that even though life span is a very complicated trait caused by variation on a large number of loci, [...] the number of loci that are in common is a totally finite number. So, we can imagine going on to the next stage and investigating one gene at a time and in combination,” Mackay said.

CLEMSON, South Carolina — Scientists believe about 25 percent of the differences in human life span is determined by genetics — with the rest determined by environmental and lifestyle factors. But they don’t yet know all the genes that contribute to a long life. A study published March 5, 2020...

03/26/2020

Our founder and host recently appeared on Living Beyond 120's podcast with Dr. Gladden and Mark.

➡️ https://livingbeyond120.com/episodes/67

Check out their discussion on the mindset needed to achieve longevity past what the rest of the world believes is an acceptable age.

03/05/2020

We are always looking for tips and tricks. Here are some from Blue Zones... They have to be doing something right!

This phrase “Blue Zones” refers to five different regions around the globe that researchers have identified as having the highest concentrations of centenarians in the world.

03/04/2020

More mainstream reporting on biological age and a nod to D50 Grand Master Dr Greg Fayh's trial

(Editor’s note: This article is part of an editorial partnership between Next Avenue and The American Federation for Aging Research (AFAR), a national nonprofit whose mission is to support and

03/04/2020

"we cannot rely on observational epidemiology" says Peter Attia, MD

Does reducing meat consumption improve health?

03/03/2020

When these new-and-improved beta cells were infused into diabetic mice, their blood sugar levels were stabilized, rendering the diabetes “functionally cured” for up to nine months.

Diabetes is characterized by trouble producing or managing insulin, and one emerging treatment involves converting stem cells into beta cells that secrete the hormone. Now, scientists have developed a more efficient method of doing just that, and found that implanting these cells in diabetic mice…

03/03/2020

"Traditional calorie restriction robustly improves markers of aging in humans."

Calorie restriction (CR) is a potent modulator of longevity in multiple species. A growing body of evidence shows that sustained periods of CR without…

03/03/2020

That's what we are talking about!!

"We are hopeful that targeting the molecular drivers of senescence will lead us to safe and effective medicines that help more people stay as healthy as possible, for as long as possible."

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus—and identified an FDA-approved drug that helped suppress the damaging effe...

03/03/2020

Our founder and host recently appeared on Living Beyond 120's podcast with Dr. Gladden and Mark.

➡️ https://livingbeyond120.com/episodes/67

Check out their discussion on the mindset needed to achieve longevity past what the rest of the world believes is an acceptable age.

02/21/2020

“With the new base-editing technique the mutation in the CFTR gene can be detected and repaired without creating further damage in the genome”

Scientists at the Hubrecht Institute in the Netherlands used base editing, an approach to CRISPR that doesn’t involve cutting DNA, to correct a gene mutation that causes cystic fibrosis (CF). They believe the study, which they performed in stem cells from CF patients, provides evidence that a dise...

02/17/2020

Our founder and host recently appeared on Living Beyond 120's podcast with Dr. Gladden and Mark.

Check out their discussion on the mindset needed to achieve longevity past what the rest of the world believes is an acceptable age.

On this episode of Living Beyond 120, Mark and Dr. Gladden welcome Richard Rossi, the founder of daVinci50, a Mastermind group of celebrated doctors, Harvard scientists, and world-renowned biohackers who are achieving the big breakthroughs and getting the big results in ultra-healthy life extension....

02/13/2020